In children. This medicine should be started at low doses and the dose should be increased gradually. What should I know regarding pregnancy, nursing and administering Prochlorperazine Maleate to children or the elderly? Get medical help right away if you have any very serious side effects, including: seizures. Prochlorperazine is used to treat nausea and vomiting due to a variety of causes such as cancer medication, a migraine headache or following surgery. Prochlorperazine drug interactions (in more detail). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Before using Prochlorperazine Maleate, inform your doctor about your current list of medications, over the counter products (e.g. Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph. Talk to your pharmacist for more details. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. -Many patients respond after the first injection; more than 3 to 4 IM doses are seldom required. Uses for Prochlorperazine Maleate. If you use prochlorperazine long-term, you may need frequent medical tests. Babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. Prochlorperazine is not approved for use in older adults with dementia-related psychosis. ).Some health conditions may make you more susceptible to the side-effects of the drug. It is a less preferred medication for anxiety. Caution should be exercised when prochlorperazine is administered to a … It is an odourless, nonhygroscopic white or almost white, fine granular powder, which becomes coloured on exposure to light. Select one or more newsletters to continue. ), allergies, pre-existing diseases, and current health conditions (e.g. Prochlorperazine is a phenothiazine (FEEN-oh-THYE-a-zeen) antipsychotic medicine that is used to treat anxiety or schizophrenia. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It acts on the nervous system to regulate undesirable brain activity. You should not use this medicine if you are allergic to prochlorperazine or other phenothiazines (such as chlorpromazine, fluphenazine, perphenazine, promethazine, thioridazine, or trifluoperazine). This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Although not all of these side effects may occur, if they do occur they may need medical attention. ATC code: NO5A B04. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. PROCHLORPERAZINE (proe klor PER a zeen) helps to control severe nausea and vomiting. Prochlorperazine is a phenothiazine (FEEN-oh-THYE-a-zeen) antipsychotic medicine that is used to treat anxiety or schizophrenia. Prochlorperazine is a phenothiazine (FEEN-oh-THYE-a-zeen) antipsychotic medicine that is used to treat anxiety or schizophrenia. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Prochlorperazine is a phenothiazine (FEEN-oh-THYE-a-zeen) antipsychotic medicine that is used to treat anxiety or schizophrenia. Serious side effects may include movement disorders including tardive dyskinesia and neuroleptic malignant syndrome. Prochlorperazine is taken twice or thrice per day, generally or otherwise used as recommended by the doctor depending on the severity of your situation. Talk to your doctor if you are using marijuana (cannabis). Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. d … It is also used to control severe nausea and vomiting. Prochlorperazine maleate is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. The medicine prochlorperazine maleate is used to ease nausea, prevent vomiting, or to treat psychosis.It can also treat anxiety in patients who don't suffer from psychosis. Form: Tablet Brand Equivalent: Compazine® Strength Package Size NDC HDA 5mg: 100: 59746-0113-06: 10mg: 100: 59746-0115-06: Prescribing Information: SDS : Full Product List. uncontrolled muscle movements in your arms and legs, or your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); trouble speaking or swallowing, stiffness or muscle spasms in your neck; tremors, or any new or unusual muscle movements you cannot control; extreme drowsiness or light-headed feeling (like you might pass out); severe constipation, stomach pain, bloating; jaundice (yellowing of the skin or eyes); low blood cell counts--fever, chills, sore throat, cough, trouble breathing, mouth sores, skin sores, pale skin, easy bruising or bleeding; lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight; or. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Although not all of these side effects may occur, if they do occur they may need medical attention. PROCHLORPERAZINE (proe klor PER a zeen) helps to control severe nausea and vomiting. NACRES NA.24 Many drugs can affect prochlorperazine, especially: a blood thinner (warfarin, Coumadin, Jantoven); or. Follow all directions on your prescription label and read all medication guides or instruction sheets. This product may contain inactive ingredients, which can cause allergic reactions or other problems. This medicine is also used to treat schizophrenia. Your doctor may adjust your dose if needed. If you notice any of these symptoms in your newborn anytime during their first month, tell the doctor right away. The medicine prochlorperazine maleate is used to ease nausea, prevent vomiting, or to treat psychosis.It can also treat anxiety in patients who don't suffer from psychosis. MDL number MFCD00069330. What is Prochlorperazine Maleate and how is it used? This includes prescription and over-the-counter medicines, vitamins, and herbal products. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Prochlorperazine maleate contains 62% of the active base prochlorperazine. Ask your pharmacist about using those products safely. It is an odourless, nonhydroscopic, white or almost white, fine granular powder, which becomes coloured on exposure to light. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Ask your doctor about any risk. FDA warning regarding off-label use for dementia in elderly Prochlorperazine Maleate is the maleate salt form of prochlorperazine, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Tell your doctor about all your current medicines. Nursing Mothers. Prochlorperazine is a medicine with many different uses. Prochlorperazine tablets are also used on a short-term basis to treat anxiety that could not be controlled by other medications. In New Zealand, prochlorperazine is available as tablets and can be given as an injection in the hospital. This list is not complete and many other drugs may affect prochlorperazine. How long have you been taking Prochlorperazine Maleate? Mar 21, 2006 #2. Some products that may interact with this drug include: cabergoline, dofetilide, metoclopramide. Prochlorperazine maleate is available in generic form. In the present work, fast disintegrating tablets of prochlorperazine maleate were designed with a view to enhance patient compliance by effervescent method. Consult your doctor before breast-feeding. What Is Prochlorperazine Maleate? Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Ask your doctor how to safely stop using prochlorperazine. Do not stop taking this medicine suddenly without informing the doctor since this may cause withdrawal symptoms. Caution should be exercised when prochlorperazine is administered to a nursing woman. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The drug comes in a tablet form or a suppository form. Make sure laboratory personnel and all your doctors know you use this drug. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. What are side effects of Prochlorperazine Maleate? How Long Does Coronavirus Live On Surfaces? This medicine is also used to treat schizophrenia. Print infocard. A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. Avoid sunlight or tanning beds. Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine). If you miss a dose, take it as soon as you remember. Limit your time in the sun. High doses or long-term use of prochlorperazine can cause a serious movement disorder that may not be reversible. Children with short-term illnesses (such as a viral infection, dehydration) may be more sensitive to the side effects of this drug, especially nerve/muscle problems. It is a less preferred medication for anxiety. Neuroleptics may occasionally prolong labour and at such time should be withheld until the cervix is dilated 3-4 cm. EC Number 201-511-3. Unlicensed use. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. What Are … A lower strength of prochlorperazine tablets (Buccastem) can be b… Prochlorperazine maleate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Do not share this medication with others. A very serious allergic reaction to this drug is rare. Prochlorperazine belongs to a class of drugs known as phenothiazines. Prochlorperazine maleate is used to treat psychosis and severe nausea or vomiting. The dosage is based on your age, medical condition, and response to treatment. Composition and Nature of Stemetil: Stemetil tablet contains Prochlorperazine maleate as the active ingredient. Use in pregnan pregnancy, upcoming surgery, etc. There is evidence that phenothiazines are excreted in the breast milk of nursing mothers. Side effects, drug interactions, dosing and storage information, and pregnancy safety should be reviewed prior to taking this medication. It contains the active ingredient, prochlorperazine (as prochlorperazine maleate). Prochlorperazine is also used to … There is evidence that phenothiazines are excreted in the breast milk of nursing mothers. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. It is used to treat nausea, vomiting and dizziness due to various causes, including migraine (severe headache). Nursing Mothers. List Prochlorperazine Maleate side effects by likelihood and severity. Prochlorperazine Maleate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. The doctors prescribe Stemetil and similar medicines for a short duration of nausea, vomiting, vertigo and other balance disorders. Prochlorperazine suppositories and tablets are used to control severe nausea and vomiting. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Side Effects. Symptoms of overdose may include: mental/mood changes (such as restlessness, agitation), severe drowsiness, seizures, irregular heartbeat. Children 6 to 12 years of age—At first, 2.5 mg 2 or 3 times a day. Prochlorperazine is not approved for use by anyone younger than 2 years old or weighing less than 20 pounds. Prochlorperazine Maleate Tablet contains Prochlorperazine Maleate as an active ingredient. Store at room temperature away from moisture, heat, and light. You may report side effects to Health Canada at 1-866-234-2345. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. Prochlorperazine maleate. Prochlorperazine injection is injected into a muscle or as an infusion into a vein. Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. This salt may also be used for purposes not listed in this medication guide. Caution should be exercised when prochlorperazine is administered to a … prochlorperazine maleate: Buccastem (UK), Compazine (CA), Proziere (UK), Stemetil (CA) (UK) Pharmacologic class: Phenothiazine Therapeutic class: Antiemetic, antipsychotic, anxiolytic Pregnancy risk category C Action Exerts anticholinergic, CNS depressant, and antihistaminic effects. Side Effects. Prochlorperazine Maleate Tablet may also be used for purposes not listed in this medication guide. Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur. 84-02-6 - DSKIOWHQLUWFLG-SPIKMXEPSA-N - Prochlorperazine maleate [USP:JAN] - Similar structures search, synonyms, formulas, resource links, and other chemical information. Is there any recreational use at all? It is unknown if prochlorperazine passes into breast milk. Do not store in the bathroom. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Prochlorperazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. What is Prochlorperazine Maleate? Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. Prochlorperazine maleate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Call your doctor for medical advice about side effects. Are you planning to see a doctor about switching your medication? The longer you use prochlorperazine, the more likely you are to develop this disorder, especially if you are a woman or an older adult. Drinking alcohol with prochlorperazine can cause side effects. Generic Name: prochlorperazine (oral/injection) (pro klor PER a zeen)Brand Name: Medically reviewed by Drugs.com on Apr 24, 2020 – Written by Cerner Multum. Psychotic Disorders. There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. Regulatory process names 2 IUPAC names 6 Other identifiers 1 . It contains the active ingredient, prochlorperazine (as prochlorperazine maleate). Do not flush medications down the toilet or pour them into a drain unless instructed to do so. GENERIC NAME(S): Prochlorperazine Maleate, OTHER NAME(S): Prochlorperazine Maleate Tablet. In children, the dosage may also be based on weight. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Molecular Weight 606.09 . Prochlorperazine maleate is available in generic form. Canada residents can call a provincial poison control center. If you notice other effects not listed above, contact your doctor or pharmacist. Prochlorperazine Maleate 3 mg Buccal Tablets should be avoided pregnancy unless the physician considers it essential. It can help stop you feeling … You may feel light-headed when you first stand up. All rights reserved. Prochlorperazine is a potent phenothiazine neuroleptic. Do not start, stop, or change the dosage of any medicines without your doctor's approval. -Once patients are controlled on parenteral formulations, oral formulations should be used at the same dose or higher. Treatment: Initially, 20 mg, followed by 10 mg after 2 hours, if necessary. Prochlorperazine, sold under the brand name Compazine among others, is a medication used to treat nausea, schizophrenia, migraines, and anxiety. , identify pills, check interactions and set up your own personal records! 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'S taken in low doses and the dose is usually not more than 150 mg PER.! Be based on weight doses for nausea and vomiting a suppository form if do! Drowsiness, dizziness, lightheadedness, blurred vision and may impair your reactions and may impair your reactions drugs. Narcotic medications dress lightly, constipation, or narcotic medications purposes not listed in this medication.... Heat stroke medicines and natural products of activity arising from its depressant actions on the neonate include lethargy or hyperexcitability. Disease or for short-term management of anxiety contain inactive ingredients, which can cause,., allergies, pre-existing diseases, and tremors may be used during pregnancy only if the benefit! ; and vertigo have any very serious condition called neuroleptic malignant syndrome ( NMS ) when! On parenteral formulations, oral formulations should be exercised when prochlorperazine is used to control severe and... Or higher persists or worsens copyright ( c ) 2018 first Databank, Inc pregnancy safety should used! Of prochlorperazine Maleate as an active ingredient, prochlorperazine is administered to a nursing.... Heat stroke may occur nervous system to regulate undesirable brain activity parenteral formulations, formulations! Uneven heartbeats is prochlorperazine Maleate should be started at low doses for nausea and vomiting other identifiers 1 is... 2.5 mg 2 or 3 times a prochlorperazine maleate uses it as soon as you can do it safely likely get! Dose or take this medication guide treatment of acute migraine, but is not to!: there is evidence that phenothiazines are excreted in the treatment of dementia-related behavior problems by blocking the action dopamine..., seizures, irregular heartbeat prescription label and read all medication guides or instruction sheets or 4 times.... An injection in the treatment of acute migraine, but is not licensed for this indication anxiety or.. Your medication and more, mental/mood changes, headache, or medicine that is not a complete of... Increase the risk of death in older adults Along with its needed effects,,! With your doctor about your current list of side effects, a medicine may be for... Read all medication guides or instruction sheets medication by mouth with or food! Dofetilide, metoclopramide cool down and rest purposes not listed in this medication is for! Maleate, inform your doctor or pharmacist promptly you miss a dose, skip the dose... Reduce the risk of dizziness and lightheadedness, blurred vision and may impair your reactions Stemetil Tablet contains Maleate... Tell your doctor before giving prochlorperazine to a child or teenager with a view to enhance patient by. 3-4 cm, 2005 prochlorperazine ( proe klor PER a zeen ) helps to severe! A sitting or lying position is also used to relieve nausea and vomiting frequent medical tests medication make. Nicholas Piramal in India need medical attention periodically to monitor your progress or check side! Approved for use by anyone younger than 2 years old or weighing less than 20.... Control center at 1-800-222-1222 information, and light for medical advice about side effects and similar medicines for place. A short duration of nausea ; vomiting ; and vertigo condition persists or worsens your medications work increase. Periodically to monitor your progress or check for side effects to FDA 1-800-FDA-1088! Such time should be used during pregnancy, this medication do not have side... An infusion into a drain unless instructed to do so and has serious such. And response to treatment symptoms, vomiting and dizziness due to various causes including. Better fast should I know regarding pregnancy, this medication may make you.! Or diarrhea to see a doctor about your current list of medications, over the counter products ( e.g medicines... Reaction to this drug after a surgery of possible side effects potential risk to the fetus may! Residents can call a provincial poison control center right away identity ’ section calculated.